Effect of endoscopic injection sclerotherapy and variceal ligation on development of portal hypertensive gastropathy and duodenopathy.

The portal hypertensive gastropathy (PHG) and duodenopatby (PHD) define a wide spectrum of diffuse macroscopic lesions that appear in the gastric mucosa of patients with portal hypertension. Histologically, the lesions corresponded to dilated vessels in the mucosa and submucosa in the absence of erosions or inflammation. This work studied the effect oesophageal varices (OV) eradication either by endoscopic sclerotherapy and/or band ligation on PHG and PHD. Sixty portal hypertensive patients were classified into three groups: G.I- 20 patients with no history of bleeding or endo-therapy as control. G.Il- 20 patients with complete oesophageal eradication of OV by endoscopic sclerotherapy (EVL). G.III- 20 patients with complete oesophageal eradication by endoscopic sclerotherapy (ES). PHG was 55% in controls, 70% in EVL and 65% in EVL. PHG was 20% in controls, 35% in EVL and 35% in ES. PHG and PHD increased after complete eradication of the varices either by ES or EVL, but without statistical significant differences.