Metastatic Crohn Disease Manifesting as Granulomatous Cheilitis in a Patient With Well-Controlled Crohn Disease.

Crohn disease (CD) can affect any organ system outside the gastrointestinal tract, and these conditions are classified as extraintestinal manifestations and include arthritis, uveitis, and cutaneous manifestations. Cutaneous involvement includes erythema nodosum, pyoderma gangrenosum, and metastatic CD. The latter can be defined as a granulomatous skin lesion that is noncontiguous to the intestinal disease. In this article, we report a rare case of a 48-year-old woman with CD in endoscopic and clinical remission with chronic persistent orofacial granulomatosis of the lip secondary to CD, despite the absence of active intestinal disease and describe its management.