Prevalence and Risk Factors of Comorbid Type 2 Diabetes Mellitus in Adults With Severe Mental Disorders: A Retrospective Study.

BACKGROUND

The purpose of this study was to investigate the incidence of comorbid type 2 diabetes mellitus (T2DM) and its associated risk factors in adult patients with severe mental disorders (SMD) who were admitted to the Affiliated Brain Hospital of Guangzhou Medical University.

METHODS

We conducted a retrospective analysis of the clinical data of adult patients with SMD admitted to our hospital. The research comprised 5964 adult inpatients with SMD. Data were collected from 1 January 2023, to 31 December 2023. The collected data encompassed demographic details, classifications of mental disorders, hospitalization records, concomitant conditions, and pertinent laboratory findings. We performed descriptive and inferential statistical analyses to assess the prevalence of T2DM and identify associated risk factors.

RESULTS

Patients with SMD had a 10.14% frequency of concurrent T2DM. In this patient cohort, our study found that age, body mass index (BMI), hypertension, triglyceride levels and apolipoprotein B levels were important risk factors for T2DM.

CONCLUSION

The results show that T2DM is much more common in people with SMD and suggest that several clinical and demographic traits may increase the chance of developing this condition. Extensive screening and targeted treatments are necessary for this vulnerable group.