Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery · 2013
MRI pre-treatment tumour volume in maxillary complex squamous cell carcinoma treated with surgical resection.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Eley Karen A, Watt-Smith Stephen R, Boland Paul, Potter Matthew, Golding Stephen J
Аннотация
UNLABELLED: Tumour volume (Tv) measurements obtained from pre-treatment CT and MRI have increasingly shown to be more reliable predictors of outcome than TNM stage. The aim of this study was to determine the correlation of MRI calculated maxillary complex tumour volume with patient outcome.
METHODS: The medical records of 39 patients with squamous cell carcinoma involving the maxillary sinus, maxilla, hard palate and maxillary alveolus were reviewed and tumour volume measurements completed on pre-treatment MRI.
RESULTS: The mean tumour volume was 12.79 ± 24.31 cm(3). Independent samples t test was significant for increasing overall all-cause survival and decreasing tumour volume (1 year: p = 0.003; 5-year: p = 0.031). Cox regression was significant for stratified tumour volume, nodal involvement and peri-neural invasion for predicting disease-free survival.
CONCLUSIONS: MRI measured tumour volume assessment appears to be a reliable predictor of survival in patients with maxillary complex SCC treated by surgical resection.
METHODS: The medical records of 39 patients with squamous cell carcinoma involving the maxillary sinus, maxilla, hard palate and maxillary alveolus were reviewed and tumour volume measurements completed on pre-treatment MRI.
RESULTS: The mean tumour volume was 12.79 ± 24.31 cm(3). Independent samples t test was significant for increasing overall all-cause survival and decreasing tumour volume (1 year: p = 0.003; 5-year: p = 0.031). Cox regression was significant for stratified tumour volume, nodal involvement and peri-neural invasion for predicting disease-free survival.
CONCLUSIONS: MRI measured tumour volume assessment appears to be a reliable predictor of survival in patients with maxillary complex SCC treated by surgical resection.
Предметные рубрики MeSH
AgedAged, 80 and overCarcinoma, Squamous CellCause of DeathDisease-Free SurvivalFemaleFollow-Up StudiesForecastingHumansImage Processing, Computer-AssistedLymph NodesMagnetic Resonance ImagingMaleMaxillary NeoplasmsMaxillary Sinus NeoplasmsMiddle AgedNeck DissectionNeoadjuvant TherapyNeoplasm InvasivenessPalatal NeoplasmsPreoperative CarePlastic Surgery ProceduresRetrospective StudiesSurvival RateTreatment OutcomeTumor Burden