Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics · 2010
Risk factors affect the survival outcome of hard palatal and maxillary alveolus squamous cell carcinoma: 10-year review in a tertiary referral center.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Wang Tang Chuan, Hua Chun Hun, Lin Ching Chia, Tsou Yung-An, Tseng Hsien Chang, Tsai Ming Hsui
Аннотация
OBJECTIVE: Hard palatal cancer is relatively rare in the head and neck region. Treatment outcome, risk factors that lead to poor survival outcome, and treatment strategy are still controversial.
STUDY DESIGN: Retrospective study in a tertiary medical center.
RESULTS: Surgery is a better treatment strategy than concurrent chemoradiation therapy (CCRT) for achieving positive survival outcomes. We also found a higher surgical salvage rate in patients with hard palatal cancer who had local recurrence or neck relapse. Soft palate or infratemporal fossa involvement had poor outcomes. Ulcerative tumor features, tumor volumes larger than 10 mL, and local recurrent tumors that could not undergo salvage surgery also had poorer survival outcomes in our study.
CONCLUSION: Surgical management is still the first choice for patients with hard palate or alveolus squamous cell carcinomas even when patients had local or neck regional recurrence.
STUDY DESIGN: Retrospective study in a tertiary medical center.
RESULTS: Surgery is a better treatment strategy than concurrent chemoradiation therapy (CCRT) for achieving positive survival outcomes. We also found a higher surgical salvage rate in patients with hard palatal cancer who had local recurrence or neck relapse. Soft palate or infratemporal fossa involvement had poor outcomes. Ulcerative tumor features, tumor volumes larger than 10 mL, and local recurrent tumors that could not undergo salvage surgery also had poorer survival outcomes in our study.
CONCLUSION: Surgical management is still the first choice for patients with hard palate or alveolus squamous cell carcinomas even when patients had local or neck regional recurrence.
Предметные рубрики MeSH
Alveolar ProcessAntineoplastic AgentsCarcinoma, Squamous CellChemotherapy, AdjuvantCisplatinDisease-Free SurvivalFollow-Up StudiesHumansMaxillary NeoplasmsMiddle AgedNeck DissectionNeoadjuvant TherapyNeoplasm InvasivenessNeoplasm Recurrence, LocalNeoplasm StagingPalatal NeoplasmsPalate, HardPalate, SoftRadiotherapy DosageRadiotherapy, AdjuvantReoperationRetrospective StudiesRisk FactorsSalvage TherapySurvival RateTemporal BoneTreatment Outcome