Early-onset gestational pemphigoid in the first trimester: a diagnostic pitfall.

This letter reports a case of a gestational pemphigoid (GP), a rare autoimmune subepidermal blistering disorder, typically arising in the third trimester of pregnancy. Early-onset presentations, during the first trimester, are exceptionally uncommon and may mimic other pregnancy-related dermatoses, delaying diagnosis. We report a rare early-onset case of GP and discuss the diagnostic challenges and management implications, allowing timely diagnosis and treatment, reducing maternal morbidity and potential obstetric complications.