Auris, nasus, larynx · 2018
Adenoid cystic carcinoma of head and neck: A retrospective clinical analysis of a single institution.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Chang Chin-Fang, Hsieh Ming-Yu, Chen Mu-Kuan, Chou Ming-Chih
Аннотация
OBJECTIVE: In this study, patients with head and neck adenoid cystic carcinoma were investigated with respect to disease characteristics, treatments, and potentially prognostic variables.
MATERIALS AND METHODS: Between January 1995 and December 2010, 29 patients with ACC of the head and neck treated at our institution were retrospectively reviewed.
RESULTS: The 29 patients had a mean age of 54.7 years. Of the 29 patients, 4 (13.8%) underwent surgical resection only, 21 (72.4%) underwent surgery with radiotherapy, and 4 (13.8%) received postoperative chemoradiotherapy. Of 9 patients (31.0%) who experienced a recurrence within the follow-up period, 3 (10.3%) had local recurrence and 5 (17.2%) had distant metastasis; 1 (3.4%) patient had both local recurrence and distant metastatic spread.
CONCLUSION: ACC is a relatively rare tumor associated with long survival, even in metastatic settings. Despite aggressive therapy with surgery, radiotherapy, and chemo- therapy, a marked potential for local and distant recurrence still remains.
MATERIALS AND METHODS: Between January 1995 and December 2010, 29 patients with ACC of the head and neck treated at our institution were retrospectively reviewed.
RESULTS: The 29 patients had a mean age of 54.7 years. Of the 29 patients, 4 (13.8%) underwent surgical resection only, 21 (72.4%) underwent surgery with radiotherapy, and 4 (13.8%) received postoperative chemoradiotherapy. Of 9 patients (31.0%) who experienced a recurrence within the follow-up period, 3 (10.3%) had local recurrence and 5 (17.2%) had distant metastasis; 1 (3.4%) patient had both local recurrence and distant metastatic spread.
CONCLUSION: ACC is a relatively rare tumor associated with long survival, even in metastatic settings. Despite aggressive therapy with surgery, radiotherapy, and chemo- therapy, a marked potential for local and distant recurrence still remains.
Предметные рубрики MeSH
AdultAgedCarcinoma, Adenoid CysticChemoradiotherapy, AdjuvantEar NeoplasmsFemaleHead and Neck NeoplasmsHumansLymphatic MetastasisMaleMiddle AgedNasopharyngeal NeoplasmsNeck DissectionNeoplasm InvasivenessNeoplasm MetastasisNeoplasm Recurrence, LocalNeoplasm StagingNose NeoplasmsOropharyngeal NeoplasmsOtorhinolaryngologic Surgical ProceduresParanasal Sinus NeoplasmsParotid NeoplasmsPrognosisRadiotherapy, AdjuvantRetrospective StudiesSalivary Gland NeoplasmsSalivary Glands, MinorSubmandibular Gland NeoplasmsSurvival Rate