Psychiatrische Praxis · 2005
[Amisulpride in Huntington's disease].
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Saft Carsten, Andrich Jürgen, Kraus Peter H, Przuntek Horst
Аннотация
OBJECTIVES: Amisulpride is a substituted benzamide derivative with atypical antipsychotic properties and low side effects.
METHOD: We report four cases of patients with clinically and genetically established Huntington's disease and signs of psychosis who were treated with Amisulpride.
RESULTS: Two patients developed extrapyramidal side effects due to the treatment. The antipsychotic therapy of all patients was effective.
DISCUSSION: Due to degeneration of striatal neurons patients suffering from Huntington's disease react early with development of extrapyramidal side effects after therapy with amisulpride.
METHOD: We report four cases of patients with clinically and genetically established Huntington's disease and signs of psychosis who were treated with Amisulpride.
RESULTS: Two patients developed extrapyramidal side effects due to the treatment. The antipsychotic therapy of all patients was effective.
DISCUSSION: Due to degeneration of striatal neurons patients suffering from Huntington's disease react early with development of extrapyramidal side effects after therapy with amisulpride.
Предметные рубрики MeSH
AgedAmisulprideAntipsychotic AgentsDelusionsDose-Response Relationship, DrugDrug Administration ScheduleDrug Therapy, CombinationFemaleFollow-Up StudiesHumansHuntington DiseaseMaleMiddle AgedNeurologic ExaminationNeuropsychological TestsParkinson Disease, SecondaryPsychotic DisordersSulpirideTreatment Outcome