Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2014
[Clinical features of peripheral neuropathy in paraproteinemic hemoblastosis].
Аннотация на английскомСтатьяНазвание и аннотация: Оригинал на русском
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Yakovlev A A, Yakovleva M V
Аннотация
OBJECTIVE: Peripheral neuropathy often occurs as a side effect of medication or as a manifestation of system disease. The purpose of this study was to evaluate the features of polyneuropathy with verified paraproteinemic hemoblastosis.
MATERIAL AND METHODS: We studied 104 patients, 72 women 32 men, aged 24-79 years. Along with neurological examination, authors studied vibration sensitivity and used electromyography and several scales for assessment of pain syndrome and other clinical presentations. RESULTS AND СONCLUSION: Clinical variants of peripheral neuropathy - neuropathy associated with paraproteinemia and neuropathy during treatment of advanced multiple myeloma with bortezomib (bortezomib-induced neuropathy), were singled out. An algorithm for the examination and treatment of patients with peripheral neuropathy was proposed.
MATERIAL AND METHODS: We studied 104 patients, 72 women 32 men, aged 24-79 years. Along with neurological examination, authors studied vibration sensitivity and used electromyography and several scales for assessment of pain syndrome and other clinical presentations. RESULTS AND СONCLUSION: Clinical variants of peripheral neuropathy - neuropathy associated with paraproteinemia and neuropathy during treatment of advanced multiple myeloma with bortezomib (bortezomib-induced neuropathy), were singled out. An algorithm for the examination and treatment of patients with peripheral neuropathy was proposed.