Stomach wall slough and ulcer perforation following endoscopic injection hemostasis with polidocanol.

A case is reported of progressive inner layer slough of the stomach antrum resulting in free perforation following endoscopic injection hemostasis of ulcer bleeding using a total of 5 ml polidocanol. This rare complication necessitated gastric resection. Relevant etiologic factors favoring this type of tissue response to endoscopic treatment are discussed.