Ocular immunology and inflammation · 2013
Uveitis with myasthenia gravis--a rare association.
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Babu Kalpana, Mukhopadhyay Moupia, Murthy Krishna R
Аннотация
AIM: To report 2 cases of idiopathic anterior uveitis with coexistent myasthenia gravis.
MATERIALS AND METHODS: Retrospective case reports.
RESULTS: A 60-year-old male and a 40-year-old male presented with chronic nongranulomatous anterior uveitis of unknown etiology. The latter had a history of hypothyroidism. During follow-up examinations, they developed bilateral ptosis. Neuromuscular conduction studies revealed systemic myasthenia in the former and ocular myasthenia in the later. Both the cases responded well to oral steroids and immunosuppressants.
CONCLUSIONS: The authors report two interesting case reports of idiopathic anterior uveitis with coexistent myasthenia gravis. In patients with chronic anterior uveitis who develop ptosis, it may be worthwhile to perform an ice test and appropriate laboratory studies and/or nerve conduction imaging to rule out myasthenia.
MATERIALS AND METHODS: Retrospective case reports.
RESULTS: A 60-year-old male and a 40-year-old male presented with chronic nongranulomatous anterior uveitis of unknown etiology. The latter had a history of hypothyroidism. During follow-up examinations, they developed bilateral ptosis. Neuromuscular conduction studies revealed systemic myasthenia in the former and ocular myasthenia in the later. Both the cases responded well to oral steroids and immunosuppressants.
CONCLUSIONS: The authors report two interesting case reports of idiopathic anterior uveitis with coexistent myasthenia gravis. In patients with chronic anterior uveitis who develop ptosis, it may be worthwhile to perform an ice test and appropriate laboratory studies and/or nerve conduction imaging to rule out myasthenia.