Khirurgiia · 2025
[Efficacy and safety of pancreatic stenting in acute biliary pancreatitis].
Аннотация на английскомСтатьяНазвание и аннотация: Оригинал на русском
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Khripun A I, Alimov A N, Orlov S Yu, Chelyapina T P, Monakhov M V, Olenichev A M, Kudryavitskii E E
Аннотация
OBJECTIVE: To evaluate the efficacy and safety of early pancreatic stenting in patients with acute biliary pancreatitis.
MATERIAL AND METHODS: We retrospectively analyzed the effect of early (within 48 hours after admission) pancreatic stenting on severity of disease, incidence of complications, mortality and hospital-stay in patients with severe acute biliary pancreatitis. Moreover, there were patients with acute biliary pancreatitis who underwent delayed endoscopic retrograde intervention and only conservative therapy.
RESULTS: Early pancreatic stenting reduced the risk of local (p=0.047) and systemic complications (p=0.027) compared to delayed intervention and conservative treatment. Early pancreatic stenting contributed to shorter hospital-stay when compared with delayed intervention (p=0.038). There was no between-group difference in mortality or severity of disease. Pancreatic stenting after 48 hours had no advantages over early stenting or conservative treatment, but significantly increased the risk of infected pancreatic necrosis (p=0.023).
CONCLUSION: Early pancreatic stenting seems to be safe and effective procedure in reducing the number of complications in patients with acute biliary pancreatitis. Neither early nor late pancreatic stenting has a significant effect on disease severity, mortality and hospital-stay.
MATERIAL AND METHODS: We retrospectively analyzed the effect of early (within 48 hours after admission) pancreatic stenting on severity of disease, incidence of complications, mortality and hospital-stay in patients with severe acute biliary pancreatitis. Moreover, there were patients with acute biliary pancreatitis who underwent delayed endoscopic retrograde intervention and only conservative therapy.
RESULTS: Early pancreatic stenting reduced the risk of local (p=0.047) and systemic complications (p=0.027) compared to delayed intervention and conservative treatment. Early pancreatic stenting contributed to shorter hospital-stay when compared with delayed intervention (p=0.038). There was no between-group difference in mortality or severity of disease. Pancreatic stenting after 48 hours had no advantages over early stenting or conservative treatment, but significantly increased the risk of infected pancreatic necrosis (p=0.023).
CONCLUSION: Early pancreatic stenting seems to be safe and effective procedure in reducing the number of complications in patients with acute biliary pancreatitis. Neither early nor late pancreatic stenting has a significant effect on disease severity, mortality and hospital-stay.