American journal of surgery · 2025
Exploring the role of quality of life in surgical decision making for patients undergoing pancreatectomy.
СтатьяМногоцентровое исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Manisundaram Naveen, Portuondo Jorge I, Chen Carolyn, Bloomston Mark, Schmidt Carl R, Zyromski Nicholas J, Ball Chad G, Morgan Katherine A, Hughes Steven J, Karanicolas Paul J, Allendorf John D, Vollmer Charles M, Brown Kimberly M, Velanovich Vic, Wood Amy, Chai Christy, Hsu Cary, Silberfein Eric, Barakat Omar, Van Buren George, Fisher William E, Erstad Derek, Camp E Ramsay
Аннотация
INTRODUCTION: The influence of baseline health-related quality of life (HRQoL) on peri-operative outcomes in pancreatobiliary (PB) patients is not well established. This study investigated the impact of baseline HRQoL on peri-operative outcomes and the effect of surgery on HRQoL.
METHODS: A secondary post-hoc analysis of a multicenter trial (2011-2016) assessed PB patients undergoing pancreatectomy. Pre-operative and 30-day post-operative FACT-G surveys were analyzed. Logistic regressions determined associations between baseline HRQoL scores and 60-day major complications. Subgroup analysis evaluated change in HRQoL (pre-operative to 30-day scores).
RESULTS: Among 391 patients, higher baseline HRQoL (FACT-G overall OR 0.54,p = 0.04) was associated with decreased likelihood of developing major complications. Surgery resulted in improvement in HRQoL for patients with chronic pancreatitis (10.2 points) compared to other pathologies (-7 to 3.9 points).
CONCLUSION: Baseline HRQoL was associated with post-operative complications and HRQoL significantly improved for patients with chronic pancreatitis, highlighting the importance of HRQoL on patient-centered outcomes.
METHODS: A secondary post-hoc analysis of a multicenter trial (2011-2016) assessed PB patients undergoing pancreatectomy. Pre-operative and 30-day post-operative FACT-G surveys were analyzed. Logistic regressions determined associations between baseline HRQoL scores and 60-day major complications. Subgroup analysis evaluated change in HRQoL (pre-operative to 30-day scores).
RESULTS: Among 391 patients, higher baseline HRQoL (FACT-G overall OR 0.54,p = 0.04) was associated with decreased likelihood of developing major complications. Surgery resulted in improvement in HRQoL for patients with chronic pancreatitis (10.2 points) compared to other pathologies (-7 to 3.9 points).
CONCLUSION: Baseline HRQoL was associated with post-operative complications and HRQoL significantly improved for patients with chronic pancreatitis, highlighting the importance of HRQoL on patient-centered outcomes.