Veterinary research communications · 2025
Clinical and pathological characterization of a feline intestinal large granular lymphocyte lymphoma (LGLL).
СтатьяКлинический случайНазвание и аннотация: Перевод пока не подготовлен
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Amaral Camila Issa, Bezerra Lorena Santos, de Jesus Nascimento Acácia Eduarda, da Silva Nayara Toledo, Borges Lize Amanda Basaglia, da Silva Paloma Helena Sanches, Barbosa Letícia Monteiro, Nepomuceno Anelise Carvalho, Dos Santos Horta Rodrigo, Cassali Geovanni Dantas, Oliveira Ayisa Rodrigues
Аннотация
A five-year-old neutered male domestic cat presented with a three-month history of vomiting, hyporexia, progressive weight loss, and abdominal pain. Ultrasound revealed a significant increase in the thickness of the ileum, suggestive of a neoplastic process. Enterectomy and enteroanastomosis was performed, and the sample was sent for histopathological examination. Grossly, the intestine was tortuous and was irregular. In the antimesenteric portion, a 1.4 cm thick, annular, homogenous, white and soft mass was present slightly reducing luminal diameter. Histologically, the neoplastic cells were arranged in sheets of large and pleomorphic round cells with numerous intracytoplasmic eosinophilic granules extending from the lamina propria to the serosa. Tumor cell immunolabelling was for CD3, multifocal for granzyme B and absent for CD79a and CD20. Based on the morphology and immunophenotyping of the neoplastic cells, the diagnosis of intestinal large granular lymphoma was made.