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Scientific data · 2026

A comprehensive European Colorectal Cancer Cohort dataset.

СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Holub Petr, Törnwall Outi, Garcia Alvarez Eva, Proynova Rumyana, Stampe Florian, Maqsood Saher, Ataian Maxmilian, Schlünder Irene, Carpén Olli, Meijer Gerrit, Nenutil Rudolf, Valík Dalibor, Parodi Barbara, Hiemstra Annemieke, Bierkens Mariska, Castanos-Vélez Esmeralda, Ückert Frank, Alexandre Diogo, Vojtíšek Ondřej, Bader Anna-Liisa, Simell Birgit, Ahern Caitlin, Horvat Vitomir, Steinfelder Erik, Gnocchi Matteo, Moscatelli Marco, Fürbaß Alexander, Horák Jiří, Frexia Francesca, Mascia Cecilia, Sulis Alessandro, Delussu Giovanni, Del Rio Mauro, Meloni Vittorio, Pireddu Luca, Leo Simone, Piras Marco Enrico, Kačenga Martin, Gofflot Stéphanie, Mate Sebastian, Prokosch Hans-Ulrich, Romano Paolo, Pistillo Daniela, Hoffmeister Michael, Brobeil Alexander, Kugic Amila, Huppertz Berthold, Paleari Valentina, Müller Heimo, Reihs Robert, Gemoll Timo, Bantel Yannick, Sjöblom Tobias, Kyriacou Kyriacos, Martino Simona di, Ciliberto Gennaro, Kock-Schoppenhauer Ann-Kristin, Oberländer Martina, Habermann Jens K, Husmann Gabriele, Edqvist Per-Henrik D, Zlobec Inti, Berger Martin D, Boeckmann Lars, George Fabienne, Southerington Tom, Brucker Daniel P, Faugeras Laurence, Vella Joanna, Felice Alex, Pace Malcolm, Fallerini Chiara, Renieri Alessandra, Hadjisavvas Andreas, Sargsyan Karine, Loizidou Maria A, Besse-Hammer Tatiana, Vogl Franziska, Litton Jan-Eric, Hummel Michael, Zatloukal Kurt, Lavitrano Marialuisa

Аннотация

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. The Biobanking and Biomolecular Resources European Research Infrastructure (BBMRI-ERIC) established a CRC-Cohort with European coverage contributed by 26 biobanks from 12 countries. This retrospective, multi-center study contains structured and curated clinical data, supporting research on biomarkers for early detection, prognosis, and treatment. A phenotypical/clinical data model has been defined and individual-level data from 10,780 CRC patients have been collected at BBMRI-ERIC in the central data deposition service hosted as part of its services. The participating biobanks host additional data, which can be accessed on request and used to derive additional data. This mechanism has been used to extend the collected data with scans of histopathological slides to support research in artificial intelligence in digital pathology and with whole genome sequencing data to pilot a use case of the upcoming European Health Data Space (EHDS). Here we present the methodology, the quality assurance mechanisms, and the implementation of FAIR and FAIR-Health principles applied to build the CRC-Cohort.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты