Retina (Philadelphia, Pa.) · 2001
Perfluorodecalin-induced intravitreal inflammation.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Singh J, Ramaesh K, Wharton S B, Cormack G, Chawla H B
Аннотация
OBJECTIVE: To report an unusual case of intravitreal inflammation in a human eye caused by the presence of residual perfluorodecalin in a case of giant retinal tear and retinal detachment.
METHODS: The posterior capsule of the lens, which was infiltrated with deposits, was collected during surgery. The specimen was stained with hematoxylin and eosin, with periodic acid-Schiff, and for melanin. Part of it was examined with electron microscopy. Immunohistochemical staining was performed to demonstrate CD68 antigens, cytokeratin, and glial fibrillary acid protein.
RESULTS: Vacuolated macrophages and retinal pigment epithelial cells infiltrated the posterior capsule. Electron microscopy showed the presence of membrane-lined vacuoles within the macrophages. A monolayer of epithelial cells covered the cellular infiltration.
CONCLUSION: Residual perfluorodecalin can induce an intraocular chronic macrophage response.
METHODS: The posterior capsule of the lens, which was infiltrated with deposits, was collected during surgery. The specimen was stained with hematoxylin and eosin, with periodic acid-Schiff, and for melanin. Part of it was examined with electron microscopy. Immunohistochemical staining was performed to demonstrate CD68 antigens, cytokeratin, and glial fibrillary acid protein.
RESULTS: Vacuolated macrophages and retinal pigment epithelial cells infiltrated the posterior capsule. Electron microscopy showed the presence of membrane-lined vacuoles within the macrophages. A monolayer of epithelial cells covered the cellular infiltration.
CONCLUSION: Residual perfluorodecalin can induce an intraocular chronic macrophage response.
Предметные рубрики MeSH
AdultAntigens, CDAntigens, Differentiation, MyelomonocyticCryosurgeryEndophthalmitisEye DiseasesFluorocarbonsGlial Fibrillary Acidic ProteinHumansImmunoenzyme TechniquesKeratinsLens Capsule, CrystallineMacrophagesMalePhacoemulsificationReoperationRetinal DetachmentRetinal PerforationsScleral BucklingVitrectomyVitreous BodyCD68 Molecule