Gastrointestinal endoscopy · 2012
Diagnostic significance of a dilated orifice of the duodenal papilla in intraductal papillary mucinous neoplasm of the pancreas.
Оценочное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Aso Teppei, Ohtsuka Takao, Ideno Noboru, Kono Hiroshi, Nagayoshi Yosuke, Mori Yasuhisa, Ohuchida Kennoki, Ueda Junji, Takahata Shunnichi, Morimatsu Katsuya, Aishima Shinichi, Igarashi Hisato, Ito Tetsuhide, Ishigami Kousei, Mizumoto Kazuhiro, Tanaka Masao
Аннотация
BACKGROUND: A dilated orifice of the duodenal papilla found during screening endoscopy or ERCP is well-known as one of the specific findings of intraductal papillary mucinous neoplasm (IPMN). However, its clinical significance is still unclear.
OBJECTIVE: To assess the diagnostic significance of a dilated orifice of the duodenal papilla and evaluate whether this could be a factor predictive of malignancy or a subtype of IPMN.
DESIGN: Retrospective study.
SETTING: University hospital.
PATIENTS: This study involved 149 patients who underwent pancreatectomy for IPMN between January 1987 and June 2011.
INTERVENTION: ERCP.
MAIN OUTCOME MEASUREMENTS: The rate of malignant and intestinal type IPMNs in patients with and without papillary dilation.
RESULTS: A dilated orifice of the duodenal papilla was significantly associated with intestinal type IPMN (P < .001), but this finding could not predict the malignant grade of IPMN (P = .13). Multivariate analysis revealed that a dilated orifice was a significant factor for predicting intestinal type in both main duct (P = .01) and branch duct IPMNs (P < .001).
LIMITATIONS: The validity of the definition of papillary dilation, selection bias, and a retrospective study.
CONCLUSION: A dilated orifice of the duodenal papilla could be a significant factor for predicting intestinal type IPMN. This may lead to better clinical management of patients with IPMN.
OBJECTIVE: To assess the diagnostic significance of a dilated orifice of the duodenal papilla and evaluate whether this could be a factor predictive of malignancy or a subtype of IPMN.
DESIGN: Retrospective study.
SETTING: University hospital.
PATIENTS: This study involved 149 patients who underwent pancreatectomy for IPMN between January 1987 and June 2011.
INTERVENTION: ERCP.
MAIN OUTCOME MEASUREMENTS: The rate of malignant and intestinal type IPMNs in patients with and without papillary dilation.
RESULTS: A dilated orifice of the duodenal papilla was significantly associated with intestinal type IPMN (P < .001), but this finding could not predict the malignant grade of IPMN (P = .13). Multivariate analysis revealed that a dilated orifice was a significant factor for predicting intestinal type in both main duct (P = .01) and branch duct IPMNs (P < .001).
LIMITATIONS: The validity of the definition of papillary dilation, selection bias, and a retrospective study.
CONCLUSION: A dilated orifice of the duodenal papilla could be a significant factor for predicting intestinal type IPMN. This may lead to better clinical management of patients with IPMN.