Jornal vascular brasileiro · 2023
Comparative study of angiographic changes in diabetic and non-diabetic patients with peripheral arterial disease.
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Trainotti Giovanni Ortale, Mariúba Jamil Victor, Bertanha Matheus, Sobreira Marcone Lima, Yoshida Ricardo de Alvarenga, Jaldin Rodrigo Gibin, de Camargo Paula Angeleli Bueno, Yoshida Winston Bonetti
Аннотация
BACKGROUND: Diabetics are at 5-15 times greater risk of developing peripheral arterial disease (PAD) and few studies have compared risk factors and distribution and severity of arterial changes in diabetics compared with non-diabetics.
OBJECTIVES: To compare angiographic changes between diabetic and non-diabetic patients with advanced PAD and correlate them with risk factors.
METHODS: A retrospective cross-sectional study was conducted of consecutive patients undergoing lower limb arteriography for PAD (Rutherford 3-6) using TASC II and Bollinger et al. angiographic scores. Exclusion criteria were upper limb angiographies, unclear images, incomplete laboratory test results, and previous arterial surgeries. Statistical analyses included chi-square tests, Fisher's test for discrete data, and Student's t test for continuous data (significance level: p < 0.05).
RESULTS: We studied 153 patients with a mean age of 67 years, 50.9% female and 58.2% diabetics. A total of 91 patients (59%) had trophic lesions (Rutherford 5 or 6) and 62 (41%) had resting pain or limiting claudication (Rutherford 3 and 4). Among diabetics, 81.7% were hypertensive, 29.4% had never smoked, and 14% had a history of acute myocardial infarction. According to the Bollinger et al. score, infra-popliteal arteries were more affected in diabetics, especially the anterior tibial artery (p = 0.005), while the superficial femoral artery was more affected in non-diabetics (p = 0.008). According to TASC II, the most severe angiographic changes in the femoral-popliteal segment occurred in non-diabetic patients (p = 0.019).
CONCLUSIONS: The most frequently affected sectors were the infra-popliteal sectors in diabetics and the femoral sector in non-diabetics.
OBJECTIVES: To compare angiographic changes between diabetic and non-diabetic patients with advanced PAD and correlate them with risk factors.
METHODS: A retrospective cross-sectional study was conducted of consecutive patients undergoing lower limb arteriography for PAD (Rutherford 3-6) using TASC II and Bollinger et al. angiographic scores. Exclusion criteria were upper limb angiographies, unclear images, incomplete laboratory test results, and previous arterial surgeries. Statistical analyses included chi-square tests, Fisher's test for discrete data, and Student's t test for continuous data (significance level: p < 0.05).
RESULTS: We studied 153 patients with a mean age of 67 years, 50.9% female and 58.2% diabetics. A total of 91 patients (59%) had trophic lesions (Rutherford 5 or 6) and 62 (41%) had resting pain or limiting claudication (Rutherford 3 and 4). Among diabetics, 81.7% were hypertensive, 29.4% had never smoked, and 14% had a history of acute myocardial infarction. According to the Bollinger et al. score, infra-popliteal arteries were more affected in diabetics, especially the anterior tibial artery (p = 0.005), while the superficial femoral artery was more affected in non-diabetics (p = 0.008). According to TASC II, the most severe angiographic changes in the femoral-popliteal segment occurred in non-diabetic patients (p = 0.019).
CONCLUSIONS: The most frequently affected sectors were the infra-popliteal sectors in diabetics and the femoral sector in non-diabetics.