Frontiers in medicine · 2026
Co-occurrence of Vogt-Koyanagi-Harada disease, diabetic retinopathy, and advanced chronic kidney disease: a case report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Huang Yutong, Wang Yifei, Ren Qian
Аннотация
OBJECTIVE: This study aimed to report a case of Vogt-Koyanagi-Harada (VKH) disease in a 53-year-old man with renal failure and diabetes, highlighting the challenges in diagnosing VKH amidst complex systemic comorbidities.
METHODS: A case report was conducted through a retrospective review of the patient's medical history, clinical presentations, diagnostic workup, and treatment course.
RESULTS: A 53-year-old man with renal failure, hypoalbuminemia, and diabetes presented with blurred vision. Initial findings included bilateral serous retinal detachment with subretinal septa, choroidal thickening, and left eye vitreous hemorrhage, without anterior chamber inflammation. Subsequent anterior segment inflammation and a positive response to combined corticosteroids and adalimumab confirmed VKH.
CONCLUSION: This case underscores the diagnostic complexity of VKH in patients with multiple systemic conditions. Corticosteroid management in such individuals requires meticulous attention, emphasizing the need for close monitoring of blood glucose and overall systemic status during treatment.
METHODS: A case report was conducted through a retrospective review of the patient's medical history, clinical presentations, diagnostic workup, and treatment course.
RESULTS: A 53-year-old man with renal failure, hypoalbuminemia, and diabetes presented with blurred vision. Initial findings included bilateral serous retinal detachment with subretinal septa, choroidal thickening, and left eye vitreous hemorrhage, without anterior chamber inflammation. Subsequent anterior segment inflammation and a positive response to combined corticosteroids and adalimumab confirmed VKH.
CONCLUSION: This case underscores the diagnostic complexity of VKH in patients with multiple systemic conditions. Corticosteroid management in such individuals requires meticulous attention, emphasizing the need for close monitoring of blood glucose and overall systemic status during treatment.