Comparative Evaluation of Fluoride Release/Uptake and Physical Properties of Self-adhesive GC Gold Label Hybrid and Antibiotic-modified Glass Ionomer Cement: An In Vitro Study.

BACKGROUND

Scientific research continues to make progress in identifying the best practices for treating and preventing dental caries. The quest to search for an ideal restorative material has been a challenge for researchers and academicians in the fraternity of restorative dentistry.

MATERIALS AND

METHODS

A total of 90 restorative specimens were prepared and divided into two groups comprising 45 samples each: gold label hybrid (group I) and antibiotic-modified glass ionomer cement (GIC) (group II). Each group was further subdivided into three groups of 15 samples each for the evaluation of compressive strength, setting time, and fluoride release, respectively. GC label hybrid was designated as group I, and an antibiotic mixture consisting of ciprofloxacin and metronidazole (1:1) was added at 1% concentration to conventional GIC (Fuji II), which served as group II. The compressive strength was evaluated using a universal testing machine with a crosshead speed of 1 mm/minute. The setting time was measured using Vicat's apparatus. Fluoride release was evaluated using an ion-selective electrode. The data were statistically analyzed.

RESULTS

The results showed a p-value of 0.001, signifying a statistically significant difference between the two groups in terms of compressive strength, setting time, and fluoride release after 24 hours and after 1 week.

CONCLUSION

It can be concluded that antibiotic-modified GIC showed the best in vitro performance with improved characteristics, such as higher compressive strength, faster setting time, and enhanced fluoride release.

HOW TO CITE THIS ARTICLE: Done V, Battu S, Prasad MG, et al. Comparative Evaluation of Fluoride Release/Uptake and Physical Properties of Self-adhesive GC Gold Label Hybrid and Antibiotic-modified Glass Ionomer Cement: An In Vitro Study. Int J Clin Pediatr Dent 2025;18(2):146-152.