Journal of gastroenterology · 2002
A rare association of primary biliary cirrhosis and pernicious anemia.
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Aoyama Hajime, Sakugawa Hiroshi, Nakasone Hiroki, Nakayoshi Tomofumi, Kinjo Akiko, Tamayose Maki, Higa Hajime, Uema Eriko, Chinen Takayuki, Tomiyama Ryosaku, Uchima Nobufumi, Kugai Yukino, Kinjo Fukunori, Saito Atsushi, Kinjo Mitsuru
Аннотация
Primary biliary cirrhosis is often associated with autoimmune diseases. However, an association between primary biliary cirrhosis and pernicious anemia has rarely been reported. We report a patient with primary biliary cirrhosis associated with pernicious anemia and autoimmune gastritis. The patient was a 64-year-old Japanese woman who had been diagnosed as having primary biliary cirrhosis 5 years previously. She was readmitted with jaundice and macrocytic anemia. The diagnosis of pernicious anemia was confirmed by the low level of serum vitamin B12 and the presence of anti-parietal cell antibody and anti-intrinsic factor antibody. Pernicious anemia should be regarded as a possible complication of primary biliary cirrhosis.