Crohn's & colitis 360 · 2025
Rate of Participation in a Second Randomized Clinical Trial and Factors Associated with the Likelihood of Participation among IBD Patients who already Experienced a Randomized Clinical Trial.
Письмо в редакциюНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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История · было → стало
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Gabbiadini Roberto, Pitoni Demis, Bertoli Peter, Privitera Giuseppe, Dal Buono Arianna, Danieli Patrizia, Repici Alessandro, Loy Laura, Bezzio Cristina, Armuzzi Alessandro
Аннотация
BACKGROUND: To investigate the rate of participation in a second trial among inflammatory bowel disease (IBD) patients and to identify factors influencing their likelihood of re-engagement.
METHODS: Retrospective, single-center study. Multivariate logistic regression was used to identify factors associated with re-participation.
RESULTS: A total of 29.0% participated in a second trial. In ulcerative colitis, distance >100 km from the clinic and steroid use before the first trial were associated with reduced re-participation. In Crohn's disease (CD), long-standing disease and reimbursement during the first trial were associated with increased re-participation; previous CD-related surgery was associated with reduced re-participation.
CONCLUSIONS: Understanding factors affecting re-participation in IBD trials is crucial to improving patient involvement in research.
METHODS: Retrospective, single-center study. Multivariate logistic regression was used to identify factors associated with re-participation.
RESULTS: A total of 29.0% participated in a second trial. In ulcerative colitis, distance >100 km from the clinic and steroid use before the first trial were associated with reduced re-participation. In Crohn's disease (CD), long-standing disease and reimbursement during the first trial were associated with increased re-participation; previous CD-related surgery was associated with reduced re-participation.
CONCLUSIONS: Understanding factors affecting re-participation in IBD trials is crucial to improving patient involvement in research.