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Войти в исследования Head & neck · 2017
Narrow-band imaging in transoral laser surgery for early glottic cancer in relation to clinical outcome.
СтатьяВалидационное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Plaat Boudewijn E C, Zwakenberg Manon A, van Zwol Joost G, Wedman Jan, van der Laan Bernard F A M, Halmos György B, Dikkers Frederik G
Аннотация
BACKGROUND: The purpose of this study was to validate the prognostic value of adding narrow-band imaging (NBI) during transoral laser surgery (TLS) for early glottic cancer.
METHODS: In 84 patients, 93 transoral laser resections were performed for carcinoma in situ (Tcis), T1, or T2 glottic cancer. TLS was preceded by intraoperative evaluation using traditional white-light imaging (WLI) in 51 cases. In 42 cases, NBI was used in addition to WLI. Local recurrence rate and recurrence-free survival were retrospectively compared between both groups.
RESULTS: Local recurrences developed in 14% of the 93 cases: 12 of 51 patients (24%) were treated by TLS based on WLI alone, and in 1 of 42 patients (2%) in the NBI group (P < .01). Two-year recurrence-free survival was 82% in the WLI group and 98% in the NBI group (P < .05).
CONCLUSION: Additional use of NBI during TLS for early glottic cancer significantly improves clinical outcome.
METHODS: In 84 patients, 93 transoral laser resections were performed for carcinoma in situ (Tcis), T1, or T2 glottic cancer. TLS was preceded by intraoperative evaluation using traditional white-light imaging (WLI) in 51 cases. In 42 cases, NBI was used in addition to WLI. Local recurrence rate and recurrence-free survival were retrospectively compared between both groups.
RESULTS: Local recurrences developed in 14% of the 93 cases: 12 of 51 patients (24%) were treated by TLS based on WLI alone, and in 1 of 42 patients (2%) in the NBI group (P < .01). Two-year recurrence-free survival was 82% in the WLI group and 98% in the NBI group (P < .05).
CONCLUSION: Additional use of NBI during TLS for early glottic cancer significantly improves clinical outcome.
Предметные рубрики MeSH
AgedChi-Square DistributionCohort StudiesDisease-Free SurvivalFemaleGlottisHumansKaplan-Meier EstimateLaryngeal NeoplasmsLaser TherapyMaleMargins of ExcisionMiddle AgedMonitoring, IntraoperativeNarrow Band ImagingNatural Orifice Endoscopic SurgeryNeoplasm InvasivenessNeoplasm Recurrence, LocalNeoplasm StagingNetherlandsPrognosisRetrospective StudiesRisk AssessmentSurvival AnalysisTreatment Outcome