[Effect of extent of glottal incompetence on phonation in excised canine larynx models].

Objective

To compare the acoustic signal, mucosal wave and aerodynamic parameter (phonation threshold pressure, PTP) under different sub-glottal pressure (SGP) on the excised canine models with different extent of glottal incompetence.

Methods

Perturbation measures and nonlinear dynamic measures were applied to analyze the acoustic signal (jitter, shimmer), mucosal wave [frequency(F), amplitude(A), phase(P)] and PTP from our study including 11 excised canine larynges with different extent of glottal incompetence (0 mm, 1 mm, 2 mm, 3 mm, n=11, respectively) under 1-4 kPa sub-glottal pressure.

Results

There were significant differences between different groups in jitter, shimmer, amplitude, frequency and PTP under various SGPs and extent of glottal incompetence (all P<0.05), inversely, there was no significant difference in P between groups (P>0.05). Jitter and shimmer changed obviously when the SGP increased to 3 kPa in the control group and GI 1 mm group. Jitter and shimmer changed obviously when the SGP increased to 2 kPa in the GI 2 mm and 3 mm groups. The F and A of mucosal wave increased with increasing SGP, decreased with increasing GI, and the P changed irregularly. There was statistically significant difference of PTP between different GI groups.

Conclusions

The SGP and the extent of GI had obvious affection on the the acoustic signal, mucosal wave and aerodynamic parameters.