Betaine excretion correlates with plasma homocysteine when plasma lipids are elevated.

OBJECTIVES

To reconcile observing a positive correlation of betaine excretion with homocysteine in lipid disorder patients but not other study groups.

DESIGN AND

METHODS

Correlations were estimated in subgroups of a control group and the lipid disorder patients.

RESULTS

Plasma non high-density lipoprotein (non-HDL) cholesterol differed (p<0.0001) between the groups. The correlation increased with the median plasma non-HDL cholesterol in subgroups.

CONCLUSIONS

This correlation is associated with patients with elevated plasma lipids.