[Dynamics of changes in rat cerebral cortex electrical activity with neuropathic trigeminal neuralgia].

The dynamics of expressivity of spontaneous epileptiformic activity, increase of evoked potentials, afterdischarges in somatosensory cortex were studied in the rats with infraorbital nerve compression in acute experiments during 6 months. It was shown that these changes were more expressed in hemisphere, contralateral to compressed nerve and were recorded during 1 week after compression already. In the course of time frequency of the recording of the spontaneous epileptiformic activity in the rat population increased while evoked potential increase and after discharges were more expressed in 3-6 weeks after compression. This dynamics is evidence the supposition about formation of central generator of pathologically increased excitation and pathological system which includes of both hemispheres.