Monitoring complications of botulinum toxin in community practice: A pharmacological study.

Botulinum toxin is widely used for cosmetic wrinkle reduction, hyperhidrosis, chronic migraine and facial muscle disorders, but concerns persist regarding adverse effects related to injection technique, toxin diffusion and practitioner variability. Therefore, it is of interest to evaluate the complication rates of community-based botulinum toxin therapy and characterize the clinical presentations of its associated adverse effects. A prospective pharmacological observational study was conducted on 120 patients receiving botulinum toxin type A injections. Majority of complications were mild and transient, with injection-site pain and bruising representing the most common local adverse effects. Thus, data shows the botulinum toxin injections performed by trained practitioners have a favorable safety profile in community practice.