Revista de neurologia · 2003
[Sialorrhea in patients with Parkinson. A six year prospective study].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Serrano-Dueñas M
Аннотация
INTRODUCTION: The sialorrhea has been recognised as one of the manifestations of Parkinson's disease, with a frequency of up to 80%. The evolution of patients with sialorrhea is unknown.
PATIENTS AND METHODS: We study 26 male and 17 female patients with Parkinson's disease and sialorrhea.
RESULTS: Evaluation at three years showed that sialorrhea had persisting in 18 of them, at six years showed that persisted in 8 patients. We found significant impairment in the sialorrhea group.
CONCLUSION: If we accept the principle, that sialorrhea are levodopa-resistant disorders as non nigrostriatal symptoms, secondary to a diffuser and more extended cerebral stem degeneration, we could assume that in these patients with sialorrhea cortical-sub cortical circuits are more widely involved leading to motor and cognitive impairment and depression.
PATIENTS AND METHODS: We study 26 male and 17 female patients with Parkinson's disease and sialorrhea.
RESULTS: Evaluation at three years showed that sialorrhea had persisting in 18 of them, at six years showed that persisted in 8 patients. We found significant impairment in the sialorrhea group.
CONCLUSION: If we accept the principle, that sialorrhea are levodopa-resistant disorders as non nigrostriatal symptoms, secondary to a diffuser and more extended cerebral stem degeneration, we could assume that in these patients with sialorrhea cortical-sub cortical circuits are more widely involved leading to motor and cognitive impairment and depression.