Ophthalmic surgery, lasers & imaging retina · 2026
Feasibility Study of Balloon Angioplasty for the Treatment of Ophthalmic Artery Stenoses in Patients With Geographic Atrophy.
СтатьяНазвание и аннотация: Перевод в очереди
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Saravia Mario J, Rojas Jimena, de Los Santos Christan, Bazterrechea Pablo, Forgues Fernanda, Monteros Nicolas, Cortalezzi Juan Manuel, Zeolite Ignacio, Sgattoni Enrique, Zeman Luis, Vidosevich Matko, Magnano Guillermo, Zas Marcelo, Rosendi Ezequiel, Franco Jeff, Calhoun Michael W, Wilbur Luana R, Rosenfeld Philip J, Lylyk Pedro
Аннотация
BACKGROUND AND OBJECTIVE: A safety and feasibility study was conducted using balloon angioplasty to treat ophthalmic artery (OA) stenoses in patients with age-related macular degeneration (AMD) with geographic atrophy (GA).
PATIENTS AND METHODS: Patients ≥ 60 years of age received OA angioplasty using an investigational catheter system and were followed for 6 months. Changes in stenosis, best-corrected visual acuity (BCVA), MNRead acuity charts, ophthalmic imaging, and a validated questionnaire were evaluated.
RESULTS: Eleven patients were treated. All adverse events were treated as needed and resolved without sequelae. Treated patients demonstrated a mean improvement over baseline in BCVA (P = .01) and reading speed (P = .03) at study exit. Mean subfoveal choroidal thickness increased over baseline (P = .004) and fellow eyes (P = .03) through week 4, remaining above baseline at study exit. Participants reported mean improvements in both mobility and reading.
CONCLUSION: Treating OA stenoses using angioplasty in patients with GA was safe with apparent visual function benefit.
PATIENTS AND METHODS: Patients ≥ 60 years of age received OA angioplasty using an investigational catheter system and were followed for 6 months. Changes in stenosis, best-corrected visual acuity (BCVA), MNRead acuity charts, ophthalmic imaging, and a validated questionnaire were evaluated.
RESULTS: Eleven patients were treated. All adverse events were treated as needed and resolved without sequelae. Treated patients demonstrated a mean improvement over baseline in BCVA (P = .01) and reading speed (P = .03) at study exit. Mean subfoveal choroidal thickness increased over baseline (P = .004) and fellow eyes (P = .03) through week 4, remaining above baseline at study exit. Participants reported mean improvements in both mobility and reading.
CONCLUSION: Treating OA stenoses using angioplasty in patients with GA was safe with apparent visual function benefit.