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DOI 10.1002/oby.24285

Медицинская библиотека · Obesity (Silver Spring, Md.) · 2025

Functional mobility and pain are improved for 6 years after adolescent bariatric surgery.

Thivalapill Neil, Jenkins Todd M, Inge Thomas H, Xie Changchun, Courcoulas Anita P, Harmon Carroll M, Helmrath Michael A, Sisley Stephanie, Michalsky Marc P, Ryder Justin R, Teen‐Longitudinal Assessment of Bariatric Surgery (Teen‐LABS) consortium

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Аннотация

OBJECTIVE

The long-term durability of improvements in functional mobility and musculoskeletal pain for adolescents after metabolic and bariatric surgery (MBS) is unknown.

METHODS

We used the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study to determine the change in mobility and pain among adolescents who underwent MBS. From standardized 400-m walk tests, we analyzed walk time, heart rate (HR) parameters, and musculoskeletal pain.

RESULTS

The mean walk time improved from 383 s (95% CI: 368-399) prior to surgery to 351 s (95% CI: 330-372) by 6 years. The mean resting HR was 90 beats per minute (bpm; 95% CI: 87-93) preoperatively and decreased to 80 bpm (95% CI: 76-84) by 6 years. The risk of any musculoskeletal pain decreased from 37.2% (95% CI: 25.5%-48.9%) to 11.0% (95% CI: 4.3%-17.6%) by 6 years. Mediation analysis revealed that the effect of time since surgery on walk time, resting HR, and HR recovery occurred through a weight-dependent mechanism. For posttest HR and HR difference, there was both a significant weight-dependent and weight-independent mechanism. The effect of surgery on the risk of musculoskeletal pain occurred through a weight-independent mechanism.

CONCLUSIONS

Adolescents who underwent MBS experienced significant, durable improvement in mobility and pain, despite weight regain. Our models suggest that improvements may occur through a weight-independent mechanism.

Для цитирования: Thivalapill Neil, Jenkins Todd M, Inge Thomas H, Xie Changchun, Courcoulas Anita P, Harmon Carroll M, Helmrath Michael A, Sisley Stephanie, Michalsky Marc P, Ryder Justin R, Teen‐Longitudinal Assessment of Bariatric Surgery (Teen‐LABS) consortium. Functional mobility and pain are improved for 6 years after adolescent bariatric surgery.. Obesity (Silver Spring, Md.). 2025. DOI: 10.1002/oby.24285.

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