Chirurgie (Heidelberg, Germany) · 2025
[Multimodal obesity therapy-preconditioning neoadjuvant strategies prior to bariatric surgery].
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Seidemann Lena, Licari Nicolo, Dietrich Arne
Аннотация
BACKGROUND: Bariatric surgery is a key component of a multimodal treatment approach. In addition to surgery, conservative therapeutic options should be offered to promote preoperative weight loss and improve obesity-related comorbidities.
OBJECTIVE: This review aims to present available preconditioning strategies and evaluate whether and to what extent they improve pre- and postoperative weight loss and reduce perioperative risks.
MATERIALS AND METHODS: Analysis and discussion of current literature on the topic.
RESULTS: The data available are highly heterogeneous. Preoperative weight loss can be achieved through hypocaloric diets, intragastric balloon placement, or the addition of glucagon-like peptide‑1 (GLP-1) agonists to lifestyle interventions before bariatric procedures. However, studies have not yet confirmed a positive effect on perioperative risk or postoperative weight development.
CONCLUSION: Although some preconditioning strategies appear promising and are partly part of clinical routine, the current evidence base is insufficient to support uniform recommendations for preconditioning prior to bariatric surgery.
OBJECTIVE: This review aims to present available preconditioning strategies and evaluate whether and to what extent they improve pre- and postoperative weight loss and reduce perioperative risks.
MATERIALS AND METHODS: Analysis and discussion of current literature on the topic.
RESULTS: The data available are highly heterogeneous. Preoperative weight loss can be achieved through hypocaloric diets, intragastric balloon placement, or the addition of glucagon-like peptide‑1 (GLP-1) agonists to lifestyle interventions before bariatric procedures. However, studies have not yet confirmed a positive effect on perioperative risk or postoperative weight development.
CONCLUSION: Although some preconditioning strategies appear promising and are partly part of clinical routine, the current evidence base is insufficient to support uniform recommendations for preconditioning prior to bariatric surgery.