Medicine · 2020
Successful pregnancy and live birth in woman with congenital adrenal hyperplasia: A case report.
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Xiong Wei, Huang Guiqiong, Wang Xiaodong, Tan Shiqiao
Аннотация
RATIONALE: Women with congenital adrenal hyperplasia (CAH) can suffer from impaired fertility rates as a result of increased androgen secretion or impaired sex steroid production. CAH patients have lower pregnancy rate compared to normal women. Only a few cases with successful pregnancy have been reported in the literature. This report described a case of CAH with successful pregnancy and live birth.
PATIENT CONCERNS: A 23-year-old woman visited our endocrinology department for clitoral hypertrophy and primary amenorrhea.
DIAGNOSES: The patient was diagnosed as CAH.
INTERVENTION: Prednisone was initially started to improve the patient's symptoms. Then she underwent clitoral resection and vaginoplasty several months later. She continuously took the prednisolone after the operation and had been undergoing regular checkups.
OUTCOMES: She was pregnant spontaneously without assisted reproductive technology and had a successful live birth. Her baby had shown normal external genitalia with normal karyotype and normal development up to 6 years of age.
LESSONS: Some mild CAH patients with certain types can achieved successful pregnancy without any assisted reproductive technology after treatment with steroid. The pregnancy rate among CAH women who wish to conceive may be much more optimistic than previous researches.
PATIENT CONCERNS: A 23-year-old woman visited our endocrinology department for clitoral hypertrophy and primary amenorrhea.
DIAGNOSES: The patient was diagnosed as CAH.
INTERVENTION: Prednisone was initially started to improve the patient's symptoms. Then she underwent clitoral resection and vaginoplasty several months later. She continuously took the prednisolone after the operation and had been undergoing regular checkups.
OUTCOMES: She was pregnant spontaneously without assisted reproductive technology and had a successful live birth. Her baby had shown normal external genitalia with normal karyotype and normal development up to 6 years of age.
LESSONS: Some mild CAH patients with certain types can achieved successful pregnancy without any assisted reproductive technology after treatment with steroid. The pregnancy rate among CAH women who wish to conceive may be much more optimistic than previous researches.