[Features of mucosal flora associated with relapse of ulcers and acute erosive-ulcer damage to the gastroduodenal zone during an unstable course of ischemic heart disease].

There was a study of 34 patients both with an unstable course of ischemic heart disease and a recurrence of ulcer or acute gastroduodenal ulcers and erosions. Irrespective of the nature of the pathologic process 14-15 different genera and species of microorganisms with features of potential pathogenecity were revealed in the tissue samplings from the periulcerous and perierosive zones of the mucosa. The greatest frequency, quantity and fermentative activity were marked in staphylococci, streptococci, enterococci and candidas. H. pylori yielded to a number of specimens of the gastroduodenal zone microbiocenosis in this regard. A less marked activation of the microflora pathogenic potential was observed in the intact mucosa remote from the lesions as in its tissue samplings 10-12 genera and species of microorganisms were revealed. The pathomicrobiocenosis being formed there might inhibit the healing of gastroduodenal erosions and ulcers in patients with an unstable course of ischemic heart disease, which must be taken into consideration in the development of methods for their treatment and prophylaxis.