[Course of duodenal ulcer disease depending on personality type and effectiveness of differential psychotropic therapy].

AIM: To determine features of duodenal ulcer (DU) course as regards personality traits and to validate a differentiated approach to psychopharmacological correction of such patients.

MATERIAL AND

METHODS

The personality type was determined in 102 DU patients using an experimental psychological examination.

RESULTS

Among the examinees, submissive and excitable personalities predominated (56.9 vs 43.1%, respectively). Submissive personalities were anxiously accentuated, moderately psychically rigid and moderately neurotic. Morphologically, they had diffuse fundal and antral gastritis with moderate H. pylori dissemination, intact acid production, ulcer size > 1 cm. Excitable personalities had antral gastritis with moderate H. pylori dissemination, high acid production, ulcer defect 0.6-0.9 cm.

CONCLUSION

Anti-acid and eradication therapy in combination with individual psychotropic therapy (amitriptilin in submissive and nozepam in excitable personalities) reduced the time of DU healing and prevent recurrence for one year.