[Status of vegetative tone and significance of changes in it in formation of erosive-ulcer damage to the gastroduodenal zone in patients with an unstable course of ischemic heart disease].

It was shown in 60 examined patients, that the development of erosive-ulcer disorders of stomach and duodenum under unstable course of ischemic heart disease (IHD) takes place on a background of activation of the central contour of autonomic regulation, expressed sympathicotonia and reduced of vagus influences. The revealed changes of autonomic tonus can promote to arising of disorders of hemostasis, microcirculation and stomach functions what are the leading factors in pathogenesis of gastroduodenal pathology. In spite of stereotype character of autonomic disorders, the serious disorders of the terminal blood flow in gastoduodenal tissues, increase of acid-peptic activity and the reduce of mucopolysaccharides are found out only in the persons with erosions and ulcers. It testifies to the necessity of further specification of the mechanisms of its development in the patients with unstable course of IHD.