Revista medica de Chile · 2002
[Effects of Helicobacter pylori eradication on gastroesophageal reflux in patients with duodenal ulcer].
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Rollán Antonio, Giancaspero Rossana, Fuster Francisco
Аннотация
BACKGROUND: Helicobacter pylori infection is not a risk factor for gastroesophageal reflux disease and it could even be a protector factor.
AIM: To study the relationship between H pylori eradication and gastroesophageal reflux symptoms in patients with duodenal ulcer.
PATIENTS AND METHODS: One hundred eleven patients with duodenal ulcer and treated for H pylori infection were studied. In 96 patients, H pylori was successfully eradicated and were evaluated every four months with endoscopy, during the first year. Thereafter, an annual clinical assessment was performed and endoscopy was repeated only if clinically indicated.
RESULTS: Patient were followed for a mean of 41 months (range 4 months to 6 years). Twelve patients (10.8%) had esophagitis at recruitment and in nine, H pylori was eradicated. The frequency of gastroesophageal reflux symptoms or esophagitis in this group was similar to the rest of patients. During the first year, the frequency of reflux symptoms ranged from 9 to 19%. The frequency of esophagitis persisted at about 10%, although 81% of patients with esophagitis did not have it on recruitment. After the first year, the frequency of reflux symptoms declined significantly to about 8%.
CONCLUSIONS: In these patients with duodenal ulcer, gastroesophageal reflux disease had a variable evolution after H pylori eradication.
AIM: To study the relationship between H pylori eradication and gastroesophageal reflux symptoms in patients with duodenal ulcer.
PATIENTS AND METHODS: One hundred eleven patients with duodenal ulcer and treated for H pylori infection were studied. In 96 patients, H pylori was successfully eradicated and were evaluated every four months with endoscopy, during the first year. Thereafter, an annual clinical assessment was performed and endoscopy was repeated only if clinically indicated.
RESULTS: Patient were followed for a mean of 41 months (range 4 months to 6 years). Twelve patients (10.8%) had esophagitis at recruitment and in nine, H pylori was eradicated. The frequency of gastroesophageal reflux symptoms or esophagitis in this group was similar to the rest of patients. During the first year, the frequency of reflux symptoms ranged from 9 to 19%. The frequency of esophagitis persisted at about 10%, although 81% of patients with esophagitis did not have it on recruitment. After the first year, the frequency of reflux symptoms declined significantly to about 8%.
CONCLUSIONS: In these patients with duodenal ulcer, gastroesophageal reflux disease had a variable evolution after H pylori eradication.