The Journal of thoracic and cardiovascular surgery · 2003
Gender profiling in coronary artery bypass grafting.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Koch Colleen Gorman, Khandwala Farah, Nussmeier Nancy, Blackstone Eugene H
Аннотация
OBJECTIVE: Although women are reported to be at increased risk of poor outcome after coronary artery bypass grafting, female gender may simply be a marker of a high-risk profile. Therefore, the objective of this study was to characterize the difference between the female and male profiles of patients presenting for coronary artery bypass grafting.
METHODS: From January 1993 to June 2002, 15,597 patients underwent isolated coronary artery bypass grafting at a single institution. Multivariable logistic regression was used to develop a model of female gender.
RESULTS: Of 15,597 patients, 3596 (23%) were women. Eighteen variables were predictive of the female gender profile, including shorter stature, increased weight, more hypertension, insulin-treated diabetes mellitus, heart failure, and higher triglyceride and high-density lipoprotein cholesterol levels. Hematocrit, bilirubin, and creatinine values were lower in women compared with men.
CONCLUSIONS: The preoperative profiles of women and men undergoing coronary artery bypass grafting are dissimilar. Statistical modeling techniques provide a unique perspective on the preoperative profile of the female patient, who is known to be at a higher risk undergoing coronary artery bypass grafting.
METHODS: From January 1993 to June 2002, 15,597 patients underwent isolated coronary artery bypass grafting at a single institution. Multivariable logistic regression was used to develop a model of female gender.
RESULTS: Of 15,597 patients, 3596 (23%) were women. Eighteen variables were predictive of the female gender profile, including shorter stature, increased weight, more hypertension, insulin-treated diabetes mellitus, heart failure, and higher triglyceride and high-density lipoprotein cholesterol levels. Hematocrit, bilirubin, and creatinine values were lower in women compared with men.
CONCLUSIONS: The preoperative profiles of women and men undergoing coronary artery bypass grafting are dissimilar. Statistical modeling techniques provide a unique perspective on the preoperative profile of the female patient, who is known to be at a higher risk undergoing coronary artery bypass grafting.