The Malaysian journal of medical sciences : MJMS · 2009
Isosporiasis in HIV/AIDS Patients in Edo State, Nigeria.
СтатьяНазвание и аннотация: Перевод в очереди
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Olusegun Akinbo Frederick, Okaka Christopher Ehis, Luiz Dantas Machado Ricardo
Аннотация
BACKGROUND: The role of opportunistic infections in accelerating disease progression in HIV-positive individuals, leading to quick death, is still receiving serious attention. The objective of this study was to determine the prevalence of Isospora belli infections in HIV-positive patients in Edo State, Nigeria between August 2007 and March 2008.
METHODS: A total of 268 samples from HIV-positive patients and 20 samples from HIV-negative patients were processed using the modified Ziehl-Neelsen staining technique to microscopically identify the presence of I. belli oocysts.
RESULTS: The overall prevalence of the coccidian was 3.1%. Gender and age had no correlation with the prevalence of the parasite (P > 0.05). There was a significant relationship between isosporiasis and CD4+ T cell counts in HIV-positive patients (OR=11.388, 95% CI= 2.797-46.371, P=0.0004).
CONCLUSIONS: Routine investigation of I. belli in HIV-positive subjects is advocated in tertiary health institutions.
METHODS: A total of 268 samples from HIV-positive patients and 20 samples from HIV-negative patients were processed using the modified Ziehl-Neelsen staining technique to microscopically identify the presence of I. belli oocysts.
RESULTS: The overall prevalence of the coccidian was 3.1%. Gender and age had no correlation with the prevalence of the parasite (P > 0.05). There was a significant relationship between isosporiasis and CD4+ T cell counts in HIV-positive patients (OR=11.388, 95% CI= 2.797-46.371, P=0.0004).
CONCLUSIONS: Routine investigation of I. belli in HIV-positive subjects is advocated in tertiary health institutions.