Retina (Philadelphia, Pa.) · 2025
Optimizing Surgical Performance and Safety in Endoresection of Uveal Melanoma.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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Romano Mario R, Ferrara Mariantonia, Feo Alessandro, Merico Anna, Angi Martina
Аннотация
PURPOSE: To present a standardized surgical technique for endoresection of uveal melanoma minimizing the risk of serious adverse events, including fatal gas embolism.
METHODS: Ten uveal melanoma patients underwent endoresection following proton beam radiotherapy for radiotherapy-related vascular complications. Vortex veins located in correspondence of the tumor base had been cauterized at the time of tantalum markers placement. Endoresection was performed following complete 25-G vitrectomy, endolaser, and endodiathermy. The tumor was removed using a subretinal or transretinal approach depending on retinal infiltration. If needed, perfluorodecalin was injected to stabilize the retina. Fluid-silicone oil or perfluorodecalin-silicone oil exchange was performed, avoiding air.
RESULTS: Endoresection was successfully performed in all eyes with no intraoperative complications. Mean follow-up was 10.8 months ± 3.2 months. One patient was enucleated due to neovascular glaucoma. At the last follow-up, the remaining patients had the eye preserved and no signs of local recurrence or neovascular glaucoma.
CONCLUSION: Our standardized surgical technique for uveal melanoma endoresection appeared to be safe, minimizing the risk of serious intraoperative and postoperative adverse events.
METHODS: Ten uveal melanoma patients underwent endoresection following proton beam radiotherapy for radiotherapy-related vascular complications. Vortex veins located in correspondence of the tumor base had been cauterized at the time of tantalum markers placement. Endoresection was performed following complete 25-G vitrectomy, endolaser, and endodiathermy. The tumor was removed using a subretinal or transretinal approach depending on retinal infiltration. If needed, perfluorodecalin was injected to stabilize the retina. Fluid-silicone oil or perfluorodecalin-silicone oil exchange was performed, avoiding air.
RESULTS: Endoresection was successfully performed in all eyes with no intraoperative complications. Mean follow-up was 10.8 months ± 3.2 months. One patient was enucleated due to neovascular glaucoma. At the last follow-up, the remaining patients had the eye preserved and no signs of local recurrence or neovascular glaucoma.
CONCLUSION: Our standardized surgical technique for uveal melanoma endoresection appeared to be safe, minimizing the risk of serious intraoperative and postoperative adverse events.