Treatment of unstable angina pectoris with modified nuan gan jian--a report of 33 cases.

OBJECTIVE

To observe the effectiveness of Modified Nuan Gan Jian Jiao Nang (MNGJ [symbol: see text] Modified Liver-Warming Capsule) in treating unstable angina pectoris.

METHOD: Sixty-six eligible cases were assigned randomly into a treatment group and a control group and treated for 3 weeks.

RESULTS

MNGJ produced an effect in reducing episodes, improving the abnormal findings in electro-cardiogram (ECG) (P<0.05) significantly, and decreasing myocardial oxygen consumption (P<0.05). In addition, it could decrease the plasma TXB2 level and increase 6-keto-prostaglandin F1alpha (6-Keto-PGF1alpha) level (P<0.01).

CONCLUSION

MNGJ was quite effective in treating unstable angina pectoris, suggesting that the treatment of the disease could start from the liver.