Медицинская библиотека · Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2007

[Significance of C4d deposition in the follicular lymphoma].

Zheng Zhi-Yong, Bu Xian-Min, Wang Chen, Xiong Xi-Sheng, Wu Zai-Zeng, Yu Ying-Hao

Аннотация на английскомСтатьяПеревод пока не подготовлен

Аннотация

OBJECTIVE

To explore the significance of C4d deposition in follicular lymphoma (FL).

METHODS

The deposition of C4d was detected in samples from 133 cases of lymphoma by immunohistochemistry and FL was studied by the double stainings of CD35/C4d, CD21/C4d and Bcl-2/C4d,respectively.

RESULTS

Among the 26 FL tissues, irregular C4d deposition was seen in 19 tumor tissues. Double staining for CD35, CD21 or Bcl-2 showed the C4d deposition was around the follicular dendritic cells (FDC). There was no significant difference between the positive rate of C4d and the degree of lymphoma. No deposition was found in the diffuse areas of FL and other type lymphomas.

CONCLUSION

C4d deposition around the follicular dendritic cell in the neoplastic follicles is a specific indicator of follicular lymphoma.

Для цитирования: Zheng Zhi-Yong, Bu Xian-Min, Wang Chen, Xiong Xi-Sheng, Wu Zai-Zeng, Yu Ying-Hao. [Significance of C4d deposition in the follicular lymphoma].. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. 2007.

Предметные рубрики MeSH

Adolescent Adult Aged Aged, 80 and over Complement C4b Female Humans Immunohistochemistry Lymphoma, Follicular Male Middle Aged Peptide Fragments

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