IJID regions · 2026
Seroprevalence of Hepatitis B Virus and Human Immunodeficiency Virus and associated factors among pregnant women attending antenatal care in selected general hospitals of Mekelle and Eastern Zone of the Tigray Region, northern Ethiopia.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Abadi Senait Kebede, Hagos Kiflom, Shfare Mebrahtu Teweldemedhin, Abadi Angesom Kebede, Araya Tadele
Аннотация
OBJECTIVES: Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) share common transmission risk factors and remain major causes of maternal morbidity and mortality, especially in low- and middle-income countries. However, updated local data on the burden of HBV and HIV in North Ethiopia are limited. This study aimed to assess the seroprevalence of HBV and HIV and associated factors among pregnant women attending antenatal care in selected general hospitals of Mekelle and the eastern zone of Tigray, northern Ethiopia.
METHODS: A hospital-based cross-sectional study was conducted from December 2024 to April 2025 in selected general hospitals of Mekelle and the eastern zones of Tigray. Sociodemographic risk factor data and blood samples were collected from 238 pregnant women. Rapid diagnostic tests were used to detect HBV and HIV, with confirmation by enzyme-linked immunosorbent assay.
RESULTS: The overall seroprevalence of HBV and HIV were 9.7% and 4.2%, respectively. Variables like older age (adjusted odds ratio [AOR] = 3.10, 95% confidence interval [CI]: 1.01-9.46, P = 0.047), history of liver disease (AOR = 23.67, 95% CI: 3.55-158.01, P = 0.001), history of abortion (AOR = 0.24, 95% CI: 0.06-0.98, P = 0.047), nose piercing (AOR = 3.80, 95% CI: 1.33-10.88, P = 0.013), and history of sexually transmitted infections (AOR = 6.03 95% CI: 1.56-23.35; P = 0.009) had significant associations with seroprevalence of HBV, while knowledge about transmission of HIV (exact odds ratio = 0.10, 95% CI: 0.02-0.72, P = 0.0219) was the only variable significantly associated with seroprevalence of HIV in this study.
CONCLUSION: The overall seroprevalence of HBV and HIV among pregnant women attending antenatal care was high. Therefore, it is essential to implement effective prevention strategies to reduce the risk of mother-to-child transmission of these viral infections.
METHODS: A hospital-based cross-sectional study was conducted from December 2024 to April 2025 in selected general hospitals of Mekelle and the eastern zones of Tigray. Sociodemographic risk factor data and blood samples were collected from 238 pregnant women. Rapid diagnostic tests were used to detect HBV and HIV, with confirmation by enzyme-linked immunosorbent assay.
RESULTS: The overall seroprevalence of HBV and HIV were 9.7% and 4.2%, respectively. Variables like older age (adjusted odds ratio [AOR] = 3.10, 95% confidence interval [CI]: 1.01-9.46, P = 0.047), history of liver disease (AOR = 23.67, 95% CI: 3.55-158.01, P = 0.001), history of abortion (AOR = 0.24, 95% CI: 0.06-0.98, P = 0.047), nose piercing (AOR = 3.80, 95% CI: 1.33-10.88, P = 0.013), and history of sexually transmitted infections (AOR = 6.03 95% CI: 1.56-23.35; P = 0.009) had significant associations with seroprevalence of HBV, while knowledge about transmission of HIV (exact odds ratio = 0.10, 95% CI: 0.02-0.72, P = 0.0219) was the only variable significantly associated with seroprevalence of HIV in this study.
CONCLUSION: The overall seroprevalence of HBV and HIV among pregnant women attending antenatal care was high. Therefore, it is essential to implement effective prevention strategies to reduce the risk of mother-to-child transmission of these viral infections.