Terapevticheskii arkhiv · 2011
[Population association features of interleukine gene polymorphism in khakases with gastroduodenal diseases].
Сравнительное исследованиеСтатьяНазвание и аннотация: Оригинал на русском
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Ageeva E S, Shtygasheva O V, Riazantseva N V
Аннотация
AIM: To investigate association of polymorphisms of IL-1 genes and antagonist of IL-2 receptor (IL1Ra).
MATERIAL AND METHODS: Patients with chronic gastritis and ulcer were examined using the method of restriction analysis.
RESULTS: It was found that CCILbeta and R4/R4IL1Ra are most prevalent allel variants in khakas population.
CONCLUSION: It is expedient to define population risk and protective genotypes of development of ulcer associated with Helicobacter pylori in khakases.
MATERIAL AND METHODS: Patients with chronic gastritis and ulcer were examined using the method of restriction analysis.
RESULTS: It was found that CCILbeta and R4/R4IL1Ra are most prevalent allel variants in khakas population.
CONCLUSION: It is expedient to define population risk and protective genotypes of development of ulcer associated with Helicobacter pylori in khakases.