Acta gastroenterologica Latinoamericana · 2010
[Helicobacter pylori infection in Uruguayan patients of African origin: clinical, endoscopic and genetic characteristics].
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
González Nicolás, Fernández Lucía, Pérez Pérez Guillermo, Saona Gustavo, Raisler Katherine, Eugenia Torres María, Olivares Asalia, Stein Silvana, Cohen Henry
Аннотация
INTRODUCTION: Prevalence of H pylori varies in different regions around the world and its associated clinical manifestations are more severe in certain ethnic groups. Prevalence of H pylori in different groups is scarcely known in Uruguay.
OBJECTIVES: To determine the prevalence, clinical and endoscopic characteristics of H pylori infection in Uruguayan patients of African origin.
METHODS: Fifty Afro-descendant patients attending the Clinics of Gastroenterology at Hospital de Clínicas in Montevideo, were studied. They were all examined by upper endoscopy and H pylori infection was determined by histology, urease test and culture. Presence of cagA was ascertained by PCR.
RESULTS: The prevalence of H pylori infection determined by histology and urease test in Afro-descendants was 70%. No relationship was found between symptoms that led to consultation and the presence of infection. It was not possible either to establish a relationship between H pylori and endoscopic findings. CagA gene was detected in 62% of cases, but there was no relationship between its presence and the endoscopic findings.
CONCLUSIONS: The prevalence of H pylori infection in Afro-descendant Uruguayan patients is high, comparable with that found in other developing regions. However, an association of the presence of infection with symptoms or endoscopic findings was not found. CagA did not result in a risk factor for the presence of more severe gastroduodenal lesions in this group of patients.
OBJECTIVES: To determine the prevalence, clinical and endoscopic characteristics of H pylori infection in Uruguayan patients of African origin.
METHODS: Fifty Afro-descendant patients attending the Clinics of Gastroenterology at Hospital de Clínicas in Montevideo, were studied. They were all examined by upper endoscopy and H pylori infection was determined by histology, urease test and culture. Presence of cagA was ascertained by PCR.
RESULTS: The prevalence of H pylori infection determined by histology and urease test in Afro-descendants was 70%. No relationship was found between symptoms that led to consultation and the presence of infection. It was not possible either to establish a relationship between H pylori and endoscopic findings. CagA gene was detected in 62% of cases, but there was no relationship between its presence and the endoscopic findings.
CONCLUSIONS: The prevalence of H pylori infection in Afro-descendant Uruguayan patients is high, comparable with that found in other developing regions. However, an association of the presence of infection with symptoms or endoscopic findings was not found. CagA did not result in a risk factor for the presence of more severe gastroduodenal lesions in this group of patients.