Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology · 2010
[Clinical and laboratory evaluation of efficiency of Helicobacter pylori eradication].
СтатьяНазвание и аннотация: Оригинал на русском
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Drygina L B, Poiarkova N A, Sablin O A
Аннотация
AIM: To assess the efficiency of eradication therapy in long-term period using the main signs of functional activity of gastric mucosa (gastrin-17, pepsinogen I, pepsinogen II) and serum antibodies to H. pylori.
MATERIALS AND METHODS: 113 patients with chronic gastritis were examihed using clinical, endoscopic and laboratory-based methods of investigation, including GastroPanel Biohit, Finland.
RESULTS: It was observed that after 12 month of successful eradication therapy the titer of IgG to H. pylori did not exceed 60 IU/l, with pepsinogen I and pepsinogen II cut-off values set under 150 microg/l and 15 microg/l respectively.
CONCLUSION: The decrease of the titer of IgG to H. pylori and concentrations of pepsinogen I and II can be used as criteria of successful eradication therapy in long-term period.
MATERIALS AND METHODS: 113 patients with chronic gastritis were examihed using clinical, endoscopic and laboratory-based methods of investigation, including GastroPanel Biohit, Finland.
RESULTS: It was observed that after 12 month of successful eradication therapy the titer of IgG to H. pylori did not exceed 60 IU/l, with pepsinogen I and pepsinogen II cut-off values set under 150 microg/l and 15 microg/l respectively.
CONCLUSION: The decrease of the titer of IgG to H. pylori and concentrations of pepsinogen I and II can be used as criteria of successful eradication therapy in long-term period.