Limitations and suggestions for emphysematous pancreatitis: Diagnosis, treatment, and prognosis.

We read with great interest the article by Cao et al on 15 cases of emphysematous pancreatitis (EP). The study highlights the high mortality rate associated with EP and emphasizes the role of next-generation sequencing (NGS) in identifying its etiology. Additionally, it suggests treatment strategies such as antimicrobial therapy and early percutaneous catheter drainage, which may improve patient outcomes. However, we have identified certain limitations related to case selection, the evaluation of NGS technology, and the timing of computed tomography scans. To enhance the study's findings, we recommend expanding the study population, systematically evaluating the role of NGS in EP, and providing a more detailed analysis of the antibiotic initiation and duration. Furthermore, specifying the timing of computed tomography scans would improve clarity. Addressing these concerns could strengthen the study's contribution to the evidence-based management of EP, offering valuable insights for clinical practice.