Validation of the Portuguese version of the Movement Disorder Society non-motor rating scale (MDS-NMS) in Parkinson's disease.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Vale Thiago Cardoso, Santos Daniela Pereira, Oliveira Daniel Sabino de, Paula Brandão Pedro Renato de, Pereira Danilo Assis, Bouça-Machado Raquel, Silva Leonardo Oliveira, Mello Rieder Carlos Roberto de, Barbosa Egberto Reis, Cury Rubens Gisbert, Parmera Jacy Bezerra, Ghizoni Teive Hélio Afonso, Ferreira Matheus Gomes, Ferraz Henrique Ballalai, Candeias da Silva Carolina, Tumas Vitor, Nunes Cunha Ana Luiza, Braga-Neto Pedro, Lima Danielle Pessoa, Della Colleta Marcus Vinícius, Maia Débora, de Souza Fontana Marco, Damas Catarina N, Lobo Patrícia Pita, Rebordão Leonor, Magalhães Andreia D, Peralta Ana Rita, Simões Rita M, Lampreia Tânia, Velon Ana Graça, Carneiro Diogo, Raimundo Rita, Gago Miguel, Mendes Alexandre, Chã Nuno Vila, Damásio Joana, Costa Sara, Lopes Rui, Morgadinho Ana, Mestre Tiago, Stebbins Glenn T, Luo Sheng, Goetz Christopher G, Ferreira Joaquim J, Cardoso Francisco, MDS-NMS Portuguese Validation Study Group
Аннотация
METHODS: This multicenter, cross-sectional study engaged native Portuguese-speaking PD patients from 16 Movement Disorders Centers across Portugal and Brazil. We conducted a meticulous translation process into Portuguese, including forward-backward translation and cognitive pretesting. Confirmatory factor analysis (CFA) and exploratory factor analysis (EFA) were conducted to evaluate the psychometric properties and structural validity of the Portuguese version in comparison to the original English version. Tertiary analyses assessed the acceptability and reliability of domain scores within the cohort.
RESULTS: The scale was administered to 386 PD Portuguese-speaking patients. CFA, conducted with a final sample of 303 participants, confirmed that the Portuguese version maintained a factor structure consistent with the English original, with Comparative Fit Index (CFI) values meeting or exceeding the 0.90 threshold across all subscales. High CFI values in domains such as Depression, Psychosis, and Cognition underscored the robustness of the translation. EFA revealed generally strong item-factor relationships, although domains like Gastrointestinal and Non-Motor Fluctuations exhibited more complex structures. Reliability analyses demonstrated strong internal consistency, with Cronbach's α ranging from 0.50 to 0.86 across domains, further corroborated by McDonald's ω and Greatest Lower Bound values.
CONCLUSIONS: The Portuguese version of the MDS-NMS demonstrates psychometric properties and structural validity that closely aligns with the original version.