[Rinsho ketsueki] The Japanese journal of clinical hematology · 2018
[Human herpesvirus-6 pneumonitis following autologous peripheral blood stem cell transplantation].
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Saitoh Yuu, Gotoh Moritaka, Yoshizawa Seiichiro, Akahane Daigo, Fujimoto Hiroaki, Ito Yoshikazu, Ohyashiki Kazuma
Аннотация
A-46-year-old man was diagnosed with peripheral T cell lymphoma, not otherwise specified. He achieved a complete remission after pirarubicin, cyclophosphamide, vincristine, and prednisolone (THP-COP) therapy and successful autologous peripheral blood stem-cell transplantation (AutoSCT). However, 6 months post AutoSCT, he complained of fever. Chest computed tomography of the patient displayed bilateral interstitial pneumonitis. Human herpesvirus-6 (HHV-6) DNA was detected in his bronchoalveolar lavage fluid. Therefore, the patient was confirmed for HHV-6 pneumonitis. The treatment with foscarnet was effective, and no relapse was noticed in the patient. Besides, we have experienced pneumonitis of unknown origin in some patients after autologous or allogeneic stem-cell transplantations. Moreover, most of the above patients were clinically diagnosed using serum or plasma markers. Therefore, examining respiratory symptoms after AutoSCT would enable a more accurate diagnosis as well as treatment of patients with HHV-6 pneumonitis.