[Rinsho ketsueki] The Japanese journal of clinical hematology · 2017
[Peripheral T-cell lymphoma, not otherwise specified: a retrospective single-center analysis].
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Suzuki Takaharu, Kawamoto Keisuke, Tamura Suguru, Uemura Shun, Kaihatsu Akane, Nemoto Hiroki, Kobayashi Hironori, Ushiki Takashi, Fuse Kyoko, Shibazaki Yasuhiko, Moriyama Masato, Masuko Masayoshi, Narita Miwako, Sone Hirohito, Aoki Sadao, Nakamura Naoya, Oshima Koichi, Takizawa Jun
Аннотация
We retrospectively analyzed clinical and pathological features, treatments, and prognoses in 28 patients with newly diagnosed peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) in Niigata University Medical and Dental Hospital. Of them, 16 were males and 12 were females, and their median age was 62.5 (range, 26-88) years. The International Prognostic Index was high-intermediate/high in 68% of patients. Twelve patients were treated with CHOP/THP-COP and nine with third-generation chemotherapy regimens. At a median follow-up period of 30 (range: 1-164) months, the 2-year overall survival and progression-free survival rates were 61% and 44%, respectively. Further investigation of novel agents for treating PTCL-NOS is warranted.