Journal of pharmacy & bioallied sciences · 2025
Digit Ratio as Predictors of Dental Caries: A Study of the 2D:4D Relationship.
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Ishwarya M, Ananthan Vasanthakumari, Arumugam Selvabalaji, Krishnan Ekambareswaran, Umamaheswari S, Rajendran Madhumathy
Аннотация
AIM: This cross-sectional study aimed to investigate the association between caries risk and the 2D:4D ratio, a potential marker of prenatal hormone exposure, among children aged 5-12 years.
METHODS: A total of 250 children were examined. Caries indices decayed, missing and filled teeth/decayed, extracted and filled teeth (DMFT/deft) were recorded, and 2D:4D ratios were measured using a vernier caliper. Chi-square statistical analysis was conducted to explore the relationship between 2D:4D ratios and caries risk.
RESULTS: The study revealed a higher prevalence of caries among children with a low 2D:4D ratio (<1), suggesting elevated prenatal androgen levels. Specifically, 123 out of 147 individuals (83.67%) with a 2D:4D ratio less than 1 presented a high caries index, compared to 32 out of 103 individuals (31.07%) with a ratio equal to or greater than 1. Gender-specific differences were observed, with males exhibiting lower mean 2D:4D ratios than females.
CONCLUSION: These findings suggest a potential role for the 2D:4D ratio as a predictive marker for dental caries risk in children.
METHODS: A total of 250 children were examined. Caries indices decayed, missing and filled teeth/decayed, extracted and filled teeth (DMFT/deft) were recorded, and 2D:4D ratios were measured using a vernier caliper. Chi-square statistical analysis was conducted to explore the relationship between 2D:4D ratios and caries risk.
RESULTS: The study revealed a higher prevalence of caries among children with a low 2D:4D ratio (<1), suggesting elevated prenatal androgen levels. Specifically, 123 out of 147 individuals (83.67%) with a 2D:4D ratio less than 1 presented a high caries index, compared to 32 out of 103 individuals (31.07%) with a ratio equal to or greater than 1. Gender-specific differences were observed, with males exhibiting lower mean 2D:4D ratios than females.
CONCLUSION: These findings suggest a potential role for the 2D:4D ratio as a predictive marker for dental caries risk in children.